Decreased Tenofovir Diphosphate Concentrations in a Transgender Female Cohort: Implications for Human Immunodeficiency Virus Preexposure Prophylaxis

Feminizing hormone therapy (FHT) may interact with human immunodeficiency virus preexposure prophylaxis (PrEP). We found that transgender women who took FHT exhibited a 7-fold lower rectal tissue ratio of PrEP’s active metabolites vs competing deoxynucleotides compared to cisgender women and men (P...

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Bibliografiske detaljer
Udgivet i:Clin Infect Dis
Main Authors: Cottrell, Mackenzie L, Prince, Heather M A, Schauer, Amanda P, Sykes, Craig, Maffuid, Kaitlyn, Poliseno, Amanda, Chun, Tae-Wook, Huiting, Erin, Stanczyk, Frank Z, Peery, Anne F, Dellon, Evan S, Adams, Jessica L, Gay, Cindy, Kashuba, Angela D M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Brief Reports and Commentary
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188232/
https://ncbi.nlm.nih.gov/pubmed/30963179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciz290
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