Caricamento...

Reduced neurosteroid potentiation of GABA(A) receptors in epilepsy and depolarized hippocampal neurons

OBJECTIVE: Neurosteroids regulate neuronal excitability by potentiating γ‐aminobutyric acid type‐A receptors (GABARs). In animal models of temporal lobe epilepsy, the neurosteroid sensitivity of GABARs is diminished and GABAR subunit composition is altered. We tested whether similar changes occur in...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Ann Clin Transl Neurol
Autori principali: Joshi, Suchitra, Roden, William H., Kapur, Jaideep, Jansen, Laura A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187710/
https://ncbi.nlm.nih.gov/pubmed/32243088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51023
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !