Receptors with low affinity for neurosteroids and GABA contribute to tonic inhibition of granule cells in epileptic animals

Neurosteroid sensitivity of GABA(A) receptor mediated inhibition of the hippocampal dentate granule cells (DGCs) is reduced in animal models of temporal lobe epilepsy. However, the properties and subunit composition of GABA(A) receptors mediating tonic inhibition in DGCS of epileptic animals have no...

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Hlavní autoři: Rajasekaran, Karthik, Joshi, Suchitra, Sun, Chengsan, Mtchedlishvilli, Zakaria, Kapur, Jaideep
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940226/
https://ncbi.nlm.nih.gov/pubmed/20682339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.07.016
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