Receptors with low affinity for neurosteroids and GABA contribute to tonic inhibition of granule cells in epileptic animals

Neurosteroid sensitivity of GABA(A) receptor mediated inhibition of the hippocampal dentate granule cells (DGCs) is reduced in animal models of temporal lobe epilepsy. However, the properties and subunit composition of GABA(A) receptors mediating tonic inhibition in DGCS of epileptic animals have no...

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Main Authors: Rajasekaran, Karthik, Joshi, Suchitra, Sun, Chengsan, Mtchedlishvilli, Zakaria, Kapur, Jaideep
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940226/
https://ncbi.nlm.nih.gov/pubmed/20682339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.07.016
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