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Diminished Neurosteroid Sensitivity of Synaptic Inhibition and Altered Location of the α4 Subunit of GABA(A) Receptors in an Animal Model of Epilepsy

In animal models of temporal lobe epilepsy (TLE), neurosteroid sensitivity of GABA(A) receptors on dentate granule cells (DGCs) is diminished; the molecular mechanism underlying this phenomenon remains unclear. The current study investigated a mechanism for loss of neurosteroid sensitivity of synapt...

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Detalhes bibliográficos
Main Authors: Sun, Chengsan, Mtchedlishvili, Zakaria, Erisir, Alev, Kapur, Jaideep
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878477/
https://ncbi.nlm.nih.gov/pubmed/18003843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4141-07.2007
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