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Diminished Neurosteroid Sensitivity of Synaptic Inhibition and Altered Location of the α4 Subunit of GABA(A) Receptors in an Animal Model of Epilepsy

In animal models of temporal lobe epilepsy (TLE), neurosteroid sensitivity of GABA(A) receptors on dentate granule cells (DGCs) is diminished; the molecular mechanism underlying this phenomenon remains unclear. The current study investigated a mechanism for loss of neurosteroid sensitivity of synapt...

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Bibliografiske detaljer
Main Authors: Sun, Chengsan, Mtchedlishvili, Zakaria, Erisir, Alev, Kapur, Jaideep
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878477/
https://ncbi.nlm.nih.gov/pubmed/18003843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4141-07.2007
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