Reduced neurosteroid potentiation of GABA(A) receptors in epilepsy and depolarized hippocampal neurons

OBJECTIVE: Neurosteroids regulate neuronal excitability by potentiating γ‐aminobutyric acid type‐A receptors (GABARs). In animal models of temporal lobe epilepsy, the neurosteroid sensitivity of GABARs is diminished and GABAR subunit composition is altered. We tested whether similar changes occur in...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Ann Clin Transl Neurol
Main Authors: Joshi, Suchitra, Roden, William H., Kapur, Jaideep, Jansen, Laura A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187710/
https://ncbi.nlm.nih.gov/pubmed/32243088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51023
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker