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Reduced neurosteroid potentiation of GABA(A) receptors in epilepsy and depolarized hippocampal neurons
OBJECTIVE: Neurosteroids regulate neuronal excitability by potentiating γ‐aminobutyric acid type‐A receptors (GABARs). In animal models of temporal lobe epilepsy, the neurosteroid sensitivity of GABARs is diminished and GABAR subunit composition is altered. We tested whether similar changes occur in...
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| Publicado no: | Ann Clin Transl Neurol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7187710/ https://ncbi.nlm.nih.gov/pubmed/32243088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51023 |
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