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Influence of the α-Methoxy Group on the Reaction of Temocillin with Pseudomonas aeruginosa PBP3 and CTX-M-14 β-Lactamase

The prevalence of multidrug-resistant Pseudomonas aeruginosa has led to the reexamination of older “forgotten” drugs, such as temocillin, for their ability to combat resistant microbes. Temocillin is the 6-α-methoxy analogue of ticarcillin, a carboxypenicillin with well-characterized antipseudomonal...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Sacco, Michael D., Kroeck, Kyle G., Kemp, M. Trent, Zhang, Xiujun, Andrews, Logan D., Chen, Yu
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187628/
https://ncbi.nlm.nih.gov/pubmed/31685462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01473-19
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