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Dynamics and Spatial Distribution of β-Lactamase Expression in Pseudomonas aeruginosa Biofilms

The development of resistance to β-lactam antibiotics is a problem in the treatment of chronic Pseudomonas aeruginosa infection in the lungs of patients with cystic fibrosis. The main resistance mechanism is high-level expression of the chromosomally encoded AmpC β-lactamase of P. aeruginosa cells g...

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Detalhes bibliográficos
Main Authors: Bagge, Niels, Hentzer, Morten, Andersen, Jens Bo, Ciofu, Oana, Givskov, Michael, Høiby, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC375278/
https://ncbi.nlm.nih.gov/pubmed/15047517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1168-1174.2004
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