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THP-1 and Dictyostelium Infection Models for Screening and Characterization of Anti-Mycobacterium abscessus Hit Compounds

!!NCR1!! presents a great challenge to antimycobacterial therapy due to its innate resistance against most antibiotics. M. abscessus is able to grow intracellularly in human macrophages, suggesting that intracellular models can facilitate drug discovery. Thus, we have developed two host cell models:...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Richter, Adrian, Shapira, Tirosh, Av-Gay, Yossef
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187604/
https://ncbi.nlm.nih.gov/pubmed/31636068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01601-19
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