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THP-1 and Dictyostelium Infection Models for Screening and Characterization of Anti-Mycobacterium abscessus Hit Compounds

!!NCR1!! presents a great challenge to antimycobacterial therapy due to its innate resistance against most antibiotics. M. abscessus is able to grow intracellularly in human macrophages, suggesting that intracellular models can facilitate drug discovery. Thus, we have developed two host cell models:...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Richter, Adrian, Shapira, Tirosh, Av-Gay, Yossef
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187604/
https://ncbi.nlm.nih.gov/pubmed/31636068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01601-19
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