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Screening of Preselected Libraries Targeting Mycobacterium abscessus for Drug Discovery
Mycobacterium abscessus is intrinsically resistant to many antimycobacterial antibiotics, which presents serious problems in therapy. Here, we describe the development of a novel phenotype-based microscopic and computerized imaging drug screening approach. A pilot screen of 568 compounds from two li...
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| 出版年: | Antimicrob Agents Chemother |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6125491/ https://ncbi.nlm.nih.gov/pubmed/30012760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00828-18 |
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