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Screening of Preselected Libraries Targeting Mycobacterium abscessus for Drug Discovery

Mycobacterium abscessus is intrinsically resistant to many antimycobacterial antibiotics, which presents serious problems in therapy. Here, we describe the development of a novel phenotype-based microscopic and computerized imaging drug screening approach. A pilot screen of 568 compounds from two li...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Richter, Adrian, Strauch, Angelika, Chao, Joseph, Ko, Mary, Av-Gay, Yossef
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125491/
https://ncbi.nlm.nih.gov/pubmed/30012760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00828-18
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