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Screening of Preselected Libraries Targeting Mycobacterium abscessus for Drug Discovery
Mycobacterium abscessus is intrinsically resistant to many antimycobacterial antibiotics, which presents serious problems in therapy. Here, we describe the development of a novel phenotype-based microscopic and computerized imaging drug screening approach. A pilot screen of 568 compounds from two li...
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| Publicado no: | Antimicrob Agents Chemother |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6125491/ https://ncbi.nlm.nih.gov/pubmed/30012760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00828-18 |
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