Murine CD8 T‐cell functional avidity is stable in vivo but not in vitro: Independence from homologous prime/boost time interval and antigen density

It is known that for achieving high affinity antibody responses, vaccines must be optimized for antigen dose/density, and the prime/boost interval should be at least 4 weeks. Similar knowledge is lacking for generating high avidity T‐cell responses. The functional avidity (FA) of T cells, describing...

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Detaylı Bibliyografya
Yayımlandı:Eur J Immunol
Asıl Yazarlar: Gilfillan, Connie B., Wang, Chensu, Mohsen, Mona O., Rufer, Nathalie, Hebeisen, Michael, Allard, Mathilde, Verdeil, Grégory, Irvine, Darrell J., Bachmann, Martin F., Speiser, Daniel E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Adaptive immunity
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187562/
https://ncbi.nlm.nih.gov/pubmed/31785153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948355
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