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Antibody Responses Elicited through Homologous or Heterologous Prime-boost DNA and Protein Vaccinations Differ in Functional Activity and Avidity

Using a gp120 envelope glycoprotein from the JR-FL strain of human immunodeficiency virus-1 (HIV-1) as a model antigen, the goal of the current study was to evaluate the level and quality of antibody responses elicited by different prime-boost vaccination regimens (protein only, DNA only, DNA plus p...

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Detalhes bibliográficos
Main Authors: Vaine, Michael, Wang, Shixia, Hackett, Anthony, Arthos, James, Lu, Shan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847033/
https://ncbi.nlm.nih.gov/pubmed/20170767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.02.006
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