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Self-reactive T cells induce and perpetuate chronic relapsing arthritis

BACKGROUND: CD4(+) T cells play a central role during the early stages of rheumatoid arthritis (RA), but to which extent they are required for the perpetuation of the disease is still not fully understood. The aim of the current study was to obtain conclusive evidence that T cells drive chronic rela...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Tuncel, Jonatan, Holmberg, Jens, Haag, Sabrina, Hopkins, Malin Hultqvist, Wester-Rosenlöf, Lena, Carlsen, Stefan, Olofsson, Peter, Holmdahl, Rikard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187533/
https://ncbi.nlm.nih.gov/pubmed/32345366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-2104-7
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