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MHC class II alleles associated with Th1 rather than Th17 type immunity drive the onset of early arthritis in a rat model of rheumatoid arthritis

Polymorphisms in the MHC class II (MHCII) genes are strongly associated with rheumatoid arthritis, supporting the importance of autoreactive T helper (Th) cells for the development of this disease. Here, we used pristane‐induced arthritis (PIA), induced by the non‐antigenic hydrocarbon pristane, to...

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Bibliografiske detaljer
Udgivet i:Eur J Immunol
Main Authors: Tuncel, Jonatan, Haag, Sabrina, Holmdahl, Rikard
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163699/
https://ncbi.nlm.nih.gov/pubmed/28012172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201646760
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