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T cell surface redox levels determine T cell reactivity and arthritis susceptibility
Rats and mice with a lower capacity to produce reactive oxygen species (ROS) because of allelic polymorphisms in the Ncf1 gene (which encodes neutrophil cytosolic factor 1) are more susceptible to develop severe arthritis. These data suggest that ROS are involved in regulating the immune response. W...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1568933/ https://ncbi.nlm.nih.gov/pubmed/16908843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604571103 |
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