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T cell surface redox levels determine T cell reactivity and arthritis susceptibility
Rats and mice with a lower capacity to produce reactive oxygen species (ROS) because of allelic polymorphisms in the Ncf1 gene (which encodes neutrophil cytosolic factor 1) are more susceptible to develop severe arthritis. These data suggest that ROS are involved in regulating the immune response. W...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1568933/ https://ncbi.nlm.nih.gov/pubmed/16908843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604571103 |
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