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T cell surface redox levels determine T cell reactivity and arthritis susceptibility

Rats and mice with a lower capacity to produce reactive oxygen species (ROS) because of allelic polymorphisms in the Ncf1 gene (which encodes neutrophil cytosolic factor 1) are more susceptible to develop severe arthritis. These data suggest that ROS are involved in regulating the immune response. W...

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Bibliografski detalji
Glavni autori: Gelderman, Kyra A., Hultqvist, Malin, Holmberg, Jens, Olofsson, Peter, Holmdahl, Rikard
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1568933/
https://ncbi.nlm.nih.gov/pubmed/16908843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604571103
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