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Phase 1 Pharmacokinetic Study of AZD5718 in Healthy Volunteers: Effects of Coadministration With Rosuvastatin, Formulation and Food on Oral Bioavailability

AZD5718 is a first‐in‐class small‐molecule anti‐inflammatory drug with the potential to reduce the residual risk of cardiovascular events after myocardial infarction in patients receiving lipid‐lowering statin therapy. Leukotrienes are potent proinflammatory and vasoactive mediators synthesized in l...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Drug Dev
Main Authors: Ericsson, Hans, Nelander, Karin, Heijer, Maria, Kjaer, Magnus, Lindstedt, Eva‐Lotte, Albayaty, Muna, Forte, Pablo, Lagerström‐Fermér, Maria, Skrtic, Stanko
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187334/
https://ncbi.nlm.nih.gov/pubmed/31793171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.756
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