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Phase 1 Pharmacokinetic Study of AZD5718 in Healthy Volunteers: Effects of Coadministration With Rosuvastatin, Formulation and Food on Oral Bioavailability

AZD5718 is a first‐in‐class small‐molecule anti‐inflammatory drug with the potential to reduce the residual risk of cardiovascular events after myocardial infarction in patients receiving lipid‐lowering statin therapy. Leukotrienes are potent proinflammatory and vasoactive mediators synthesized in l...

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Dades bibliogràfiques
Publicat a:Clin Pharmacol Drug Dev
Autors principals: Ericsson, Hans, Nelander, Karin, Heijer, Maria, Kjaer, Magnus, Lindstedt, Eva‐Lotte, Albayaty, Muna, Forte, Pablo, Lagerström‐Fermér, Maria, Skrtic, Stanko
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187334/
https://ncbi.nlm.nih.gov/pubmed/31793171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.756
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