Design and rationale of FLAVOUR: A phase IIa efficacy study of the 5-lipoxygenase activating protein antagonist AZD5718 in patients with recent myocardial infarction

Patients with coronary artery disease remain at increased risk of recurrent life-threatening cardiovascular events even after adequate guideline-based treatment of conventional risk factors, including blood lipid levels. Inflammation is a critical pathway in the pathogenesis of atherosclerosis and i...

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Pubblicato in:Contemp Clin Trials Commun
Autori principali: Prescott, Eva, Pernow, John, Saraste, Antti, Åkerblom, Axel, Angerås, Oskar, Erlinge, David, Grove, Erik L., Hedman, Marja, Jensen, Lisette O., Svedlund, Sara, Kjaer, Magnus, Lagerström-Fermér, Maria, Gan, Li-Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451793/
https://ncbi.nlm.nih.gov/pubmed/32875138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2020.100629
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