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Mid‐manufacturing storage: Antibody stability after chromatography and precipitation based capture steps

Antibodies of the IgG2 subclass were captured from the clarified cell culture fluid either by protein A chromatography or by polyethylene glycol precipitation. The captured intermediates were stored as neutralized eluates (protein A chromatography) or in solid form as polyethylene glycol precipitate...

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Bibliografische gegevens
Gepubliceerd in:Biotechnol Prog
Hoofdauteurs: Krepper, Walpurga, Burgstaller, Daniel, Jungbauer, Alois, Satzer, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley & Sons, Inc. 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187330/
https://ncbi.nlm.nih.gov/pubmed/31622530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btpr.2928
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