Localized endothelial‐based control of platelet aggregation and coagulation under flow: A proof‐of‐principle vessel‐on‐a‐chip study

BACKGROUND: In the intact vessel wall, endothelial cells form a barrier between the blood and the remaining vascular structures, serving to maintain blood fluidity and preventing platelet activation and fibrin clot formation. The spatiotemporal space of this inhibition is largely unknown. OBJECTIVE:...

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Vydáno v:J Thromb Haemost
Hlavní autoři: Brouns, Sanne L.N., Provenzale, Isabella, van Geffen, Johanna P., van der Meijden, Paola E.J., Heemskerk, Johan W.M.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187151/
https://ncbi.nlm.nih.gov/pubmed/31863548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14719
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