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Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces
Platelet interaction with collagens, via von Willebrand factor, is a potent trigger of shear-dependent thrombus formation mediated by subsequent engagement of the signaling collagen receptor glycoprotein (GP)VI, enforced by integrin α(2)β(1). Protein tyrosine kinase Syk is central in the GPVI-induce...
Guardat en:
| Publicat a: | Int J Mol Sci |
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| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6600290/ https://ncbi.nlm.nih.gov/pubmed/31181592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20112788 |
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