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Localized endothelial‐based control of platelet aggregation and coagulation under flow: A proof‐of‐principle vessel‐on‐a‐chip study

BACKGROUND: In the intact vessel wall, endothelial cells form a barrier between the blood and the remaining vascular structures, serving to maintain blood fluidity and preventing platelet activation and fibrin clot formation. The spatiotemporal space of this inhibition is largely unknown. OBJECTIVE:...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Thromb Haemost
Hauptverfasser: Brouns, Sanne L.N., Provenzale, Isabella, van Geffen, Johanna P., van der Meijden, Paola E.J., Heemskerk, Johan W.M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187151/
https://ncbi.nlm.nih.gov/pubmed/31863548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14719
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