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Chemical‐Shift Perturbations Reflect Bile Acid Binding to Norovirus Coat Protein: Recognition Comes in Different Flavors

Bile acids have been reported as important cofactors promoting human and murine norovirus (NoV) infections in cell culture. The underlying mechanisms are not resolved. Through the use of chemical shift perturbation (CSP) NMR experiments, we identified a low‐affinity bile acid binding site of a human...

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Dettagli Bibliografici
Pubblicato in:Chembiochem
Autori principali: Creutznacher, Robert, Schulze, Eric, Wallmann, Georg, Peters, Thomas, Stein, Matthias, Mallagaray, Alvaro
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186840/
https://ncbi.nlm.nih.gov/pubmed/31644826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201900572
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