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Chemical‐Shift Perturbations Reflect Bile Acid Binding to Norovirus Coat Protein: Recognition Comes in Different Flavors

Bile acids have been reported as important cofactors promoting human and murine norovirus (NoV) infections in cell culture. The underlying mechanisms are not resolved. Through the use of chemical shift perturbation (CSP) NMR experiments, we identified a low‐affinity bile acid binding site of a human...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Creutznacher, Robert, Schulze, Eric, Wallmann, Georg, Peters, Thomas, Stein, Matthias, Mallagaray, Alvaro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186840/
https://ncbi.nlm.nih.gov/pubmed/31644826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201900572
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