A post-translational modification of human Norovirus capsid protein attenuates glycan binding

Attachment of human noroviruses to histo blood group antigens (HBGAs) is essential for infection, but how this binding event promotes the infection of host cells is unknown. Here, we employ protein NMR experiments supported by mass spectrometry and crystallography to study HBGA binding to the P-doma...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Mallagaray, Alvaro, Creutznacher, Robert, Dülfer, Jasmin, Mayer, Philipp H. O., Grimm, Lena Lisbeth, Orduña, Jose Maria, Trabjerg, Esben, Stehle, Thilo, Rand, Kasper D., Blaum, Bärbel S., Uetrecht, Charlotte, Peters, Thomas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428809/
https://ncbi.nlm.nih.gov/pubmed/30899001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09251-5
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