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Structure of Merkel Cell Polyomavirus Capsid and Interaction with Its Glycosaminoglycan Attachment Receptor

Merkel cell polyomavirus (MCPyV) is a human double-stranded DNA tumor virus. MCPyV cell entry is unique among members of the polyomavirus family as it requires the engagement of two types of glycans, sialylated oligosaccharides and sulfated glycosaminoglycans (GAGs). Here, we present crystallographi...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Bayer, Niklas J., Januliene, Dovile, Zocher, Georg, Stehle, Thilo, Moeller, Arne, Blaum, Bärbel S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527053/
https://ncbi.nlm.nih.gov/pubmed/32699083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01664-19
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