Clinical and genomic insights into circulating tumor DNA-based alterations across the spectrum of metastatic hormone-sensitive and castrate-resistant prostate cancer

BACKGROUND: Metastatic prostate cancer is a clonally heterogeneous disease state characterized by progressive somatic perturbations. The aim of this study was to identify cell free DNA- (cfDNA-) based alterations and their associations with outcomes in progressive metastatic prostate cancer. METHODS...

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Enregistré dans:
Détails bibliographiques
Publié dans:EBioMedicine
Auteurs principaux: Kohli, Manish, Tan, Winston, Zheng, Tiantian, Wang, Amy, Montesinos, Carlos, Wong, Calven, Du, Pan, Jia, Shidong, Yadav, Siddhartha, Horvath, Lisa G., Mahon, Kate L., Kwan, Edmond M., Fettke, Heidi, Yu, Jianjun, Azad, Arun A.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2020
Sujets:
Research paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186589/
https://ncbi.nlm.nih.gov/pubmed/32268276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102728
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