Fascin Activates β-Catenin Signaling and Promotes Breast Cancer Stem Cell Function Mainly Through Focal Adhesion Kinase (FAK): Relation With Disease Progression

Cancer stem cells (CSCs), a rare population of tumor cells with high self-renewability potential, have gained increasing attention due to their contribution to chemoresistance and metastasis. We have previously demonstrated a critical role for the actin-bundling protein (fascin) in mediating breast...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Barnawi, Rayanah, Al-Khaldi, Samiyah, Bakheet, Tala, Fallatah, Mohannad, Alaiya, Ayodele, Ghebeh, Hazem, Al-Alwan, Monther
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186340/
https://ncbi.nlm.nih.gov/pubmed/32373510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00440
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