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Dynamin 2 interacts with α-actinin 4 to drive tumor cell invasion

The large GTPase Dynamin 2 (Dyn2) is known to increase the invasiveness of pancreatic cancer tumor cells, but the mechanisms by which Dyn2 regulates changes in the actin cytoskeleton to drive cell migration are still unclear. Here we report that a direct interaction between Dyn2 and the actin-bundli...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Main Authors: Burton, Kevin M., Cao, Hong, Chen, Jing, Qiang, Li, Krueger, Eugene W., Johnson, Katherine M., Bamlet, William R., Zhang, Lizhi, McNiven, Mark A., Razidlo, Gina L.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185896/
https://ncbi.nlm.nih.gov/pubmed/31967944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-07-0395
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