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Dynamin 2 interacts with α-actinin 4 to drive tumor cell invasion

The large GTPase Dynamin 2 (Dyn2) is known to increase the invasiveness of pancreatic cancer tumor cells, but the mechanisms by which Dyn2 regulates changes in the actin cytoskeleton to drive cell migration are still unclear. Here we report that a direct interaction between Dyn2 and the actin-bundli...

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Publicado en:Mol Biol Cell
Autores principales: Burton, Kevin M., Cao, Hong, Chen, Jing, Qiang, Li, Krueger, Eugene W., Johnson, Katherine M., Bamlet, William R., Zhang, Lizhi, McNiven, Mark A., Razidlo, Gina L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185896/
https://ncbi.nlm.nih.gov/pubmed/31967944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-07-0395
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