Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9

Remyelination failure plays an important role in the pathophysiology of multiple sclerosis, but the underlying cellular and molecular mechanisms remain poorly understood. We now report actively demyelinating lesions in patients with multiple sclerosis are associated with increased glial expression o...

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Dades bibliogràfiques
Publicat a:Brain
Autors principals: Lindner, Maren, Thümmler, Katja, Arthur, Ariel, Brunner, Sarah, Elliott, Christina, McElroy, Daniel, Mohan, Hema, Williams, Anna, Edgar, Julia M., Schuh, Cornelia, Stadelmann, Christine, Barnett, Susan C., Lassmann, Hans, Mücklisch, Steve, Mudaliar, Manikhandan, Schaeren-Wiemers, Nicole, Meinl, Edgar, Linington, Christopher
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185739/
https://ncbi.nlm.nih.gov/pubmed/25907862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv102
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