Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9

Remyelination failure plays an important role in the pathophysiology of multiple sclerosis, but the underlying cellular and molecular mechanisms remain poorly understood. We now report actively demyelinating lesions in patients with multiple sclerosis are associated with increased glial expression o...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Lindner, Maren, Thümmler, Katja, Arthur, Ariel, Brunner, Sarah, Elliott, Christina, McElroy, Daniel, Mohan, Hema, Williams, Anna, Edgar, Julia M., Schuh, Cornelia, Stadelmann, Christine, Barnett, Susan C., Lassmann, Hans, Mücklisch, Steve, Mudaliar, Manikhandan, Schaeren-Wiemers, Nicole, Meinl, Edgar, Linington, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185739/
https://ncbi.nlm.nih.gov/pubmed/25907862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv102
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