Total CD3 T Cells Are Necessary and Sufficient to Induce Colitis in Immunodeficient Mice With Dendritic Cell–Specific Deletion of TGFbR2: A Novel IBD Model to Study CD4 and CD8 T-Cell Interaction

BACKGROUND: Inflammatory bowel disease (IBD) is a multifactorial disorder, with the innate and adaptive immune cells contributing to disease initiation and progression. However, the intricate cross-talk between immune cell lineages remains incompletely understood. The role of CD8(+) T cells in IBD p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Inflamm Bowel Dis
Päätekijät: Jamwal, Deepa Rana, Marati, Raji V, Harrison, Christy A, Midura-Kiela, Monica T, Figliuolo Paz, Vanessa R, Besselsen, David G, Ghishan, Fayez K, Kiela, Pawel R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2020
Aiheet:
Basic Science Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185689/
https://ncbi.nlm.nih.gov/pubmed/31559420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izz191
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