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Biochemical principles and inhibitors to interfere with viral capping pathways

Messenger RNAs are decorated by a cap structure, which is essential for their translation into proteins. Many viruses have developed strategies in order to cap their mRNAs. The cap is either synthetized by a subset of viral or cellular enzymes, or stolen from capped cellular mRNAs by viral endonucle...

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Detalhes bibliográficos
Publicado no:Curr Opin Virol
Main Authors: Decroly, Etienne, Canard, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185569/
https://ncbi.nlm.nih.gov/pubmed/28527860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2017.04.003
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