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The viral RNA capping machinery as a target for antiviral drugs
Most viruses modify their genomic and mRNA 5′-ends with the addition of an RNA cap, allowing efficient mRNA translation, limiting degradation by cellular 5′–3′ exonucleases, and avoiding its recognition as foreign RNA by the host cell. Viral RNA caps can be synthesized or acquired through the use of...
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| Publicado no: | Antiviral Res |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier B.V.
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7114304/ https://ncbi.nlm.nih.gov/pubmed/22841701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2012.07.007 |
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