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The viral RNA capping machinery as a target for antiviral drugs
Most viruses modify their genomic and mRNA 5′-ends with the addition of an RNA cap, allowing efficient mRNA translation, limiting degradation by cellular 5′–3′ exonucleases, and avoiding its recognition as foreign RNA by the host cell. Viral RNA caps can be synthesized or acquired through the use of...
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| Publié dans: | Antiviral Res |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier B.V.
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7114304/ https://ncbi.nlm.nih.gov/pubmed/22841701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2012.07.007 |
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