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The splicing component ISY1 regulates APE1 in base excision repair

The integrity of cellular genome is continuously challenged by endogenous and exogenous DNA damaging agents. If DNA damage is not removed in a timely fashion the replisome may stall at DNA lesions, causing fork collapse and genetic instability. Base excision DNA repair (BER) is the most important pa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:DNA Repair (Amst)
Hauptverfasser: Jaiswal, Aruna S., Williamson, Elizabeth A., Srinivasan, Gayathri, Kong, Kimi, Lomelino, Carrie L., Mckenna, Robert, Walter, Christi, Sung, Patrick, Narayan, Satya, Hromas, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185567/
https://ncbi.nlm.nih.gov/pubmed/31887540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.102769
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