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The splicing component ISY1 regulates APE1 in base excision repair
The integrity of cellular genome is continuously challenged by endogenous and exogenous DNA damaging agents. If DNA damage is not removed in a timely fashion the replisome may stall at DNA lesions, causing fork collapse and genetic instability. Base excision DNA repair (BER) is the most important pa...
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| Veröffentlicht in: | DNA Repair (Amst) |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7185567/ https://ncbi.nlm.nih.gov/pubmed/31887540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.102769 |
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