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CCL11 increases the proportion of CD4(+)CD25(+)Foxp3(+) Treg cells and the production of IL-2 and TGF-β by CD4(+) T cells via the STAT5 signaling pathway
CD4(+) regulatory T (Treg) cells are associated with immune tolerance and antitumor immunosuppression. The aim of the present study was to investigate the role and molecular mechanism of C-C motif chemokine ligand 11 (CCL11) in the regulation of Treg cells from patients with breast cancer (BC) and h...
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| Publicado no: | Mol Med Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7185287/ https://ncbi.nlm.nih.gov/pubmed/32323817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11049 |
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