Antibody targeting of B7-H4 enhances the immune response in urothelial carcinoma

Patients with locally advanced and metastatic urothelial carcinoma have a low survival rate (median 15.7 months, 13.1–17.8), with only a 23% response rate to monotherapy treatment with anti-PDL1 checkpoint immunotherapy. To identify new therapeutic targets, we profiled the immune regulatory signatur...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Podojil, Joseph R., Glaser, Alexander P., Baker, Dylan, Courtois, Elise T., Fantini, Damiano, Yu, Yanni, Eaton, Valerie, Sivajothi, Santhosh, Chiang, Mingyi, Das, Arighno, McLaughlin, Kimberly A., Robson, Paul, Miller, Stephen D., Meeks, Joshua J.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185218/
https://ncbi.nlm.nih.gov/pubmed/32363111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1744897
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