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Autophagy mediates hepatic GRK2 degradation to facilitate glucagon-induced metabolic adaptation to fasting
The liver plays a key role during fasting to maintain energy homeostasis and euglycaemia via metabolic processes mainly orchestrated by the insulin/glucagon ratio. We report here that fasting or calorie restriction protocols in C57BL6/J mice promote a marked decrease in the hepatic protein levels of...
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| Publicado no: | FASEB J |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7184883/ https://ncbi.nlm.nih.gov/pubmed/31914606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901444R |
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