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Novel Pathogenic Variant in the Cys110 Residue: A Genotype–Phenotype Report of a Patient with Norrie Disease

Norrie disease is an X-linked genetic disorder caused by pathogenic mutations in the NDP . Here, we describe the clinical phenotype and genotype in a 19-week-old male infant with bilateral retinal detachment. Whole exome sequencing using available commercial methods on the proband revealed a hemizyg...

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Detalhes bibliográficos
Publicado no:J Pediatr Genet
Main Authors: Garcha, Jaspreet, Jain, Angita, Atwal, Herjot, Sevlam, Pavalan, Atwal, Paldeep S.
Formato: Artigo
Idioma:Inglês
Publicado em: Georg Thieme Verlag KG 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183403/
https://ncbi.nlm.nih.gov/pubmed/32341821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0039-1700535
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