AAV-mediated human CNGB3 restores cone function in an all-cone mouse model of CNGB3 achromatopsia

Complete congenital achromatopsia is a devastating hereditary visual disorder. Mutations in the CNGB3 gene account for more than 50% of all known cases of achromatopsia. This work investigated the efficiency of subretinal (SR) delivered AAV8 (Y447, 733F) vector containing a human PR2.1 promoter and...

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Bibliografiske detaljer
Udgivet i:J Biomed Res
Main Authors: Zhang, Yuxin, Wang, Shanshan, Xu, Miao, Pang, Jijing, Yuan, Zhilan, Zhao, Chen
Format: Artigo
Sprog:Inglês
Udgivet: Editorial Department of Journal of Biomedical Research 2020
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183301/
https://ncbi.nlm.nih.gov/pubmed/32305965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.33.20190056
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