Transient Photoreceptor Deconstruction by CNTF Enhances rAAV-Mediated Cone Functional Rescue in Late Stage CNGB3-Achromatopsia

Achromatopsia is a genetic disorder of cones, and one of the most common forms is a channelopathy caused by mutations in the β-subunit, CNGB3, of the cone cyclic nucleotide-gated (CNG) channel. Recombinant adeno-associated virus of serotype 5 (rAAV5)-mediated gene transfer of human CNGB3 cDNA to mut...

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Bibliografiske detaljer
Main Authors: Komáromy, András M, Rowlan, Jessica S, Corr, Amanda T Parton, Reinstein, Shelby L, Boye, Sanford L, Cooper, Ann E, Gonzalez, Amaliris, Levy, Britt, Wen, Rong, Hauswirth, William W, Beltran, William A, Aguirre, Gustavo D
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677296/
https://ncbi.nlm.nih.gov/pubmed/23568263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.50
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