Safety and Biodistribution Evaluation in CNGB3-Deficient Mice of rAAV2tYF-PR1.7-hCNGB3, a Recombinant AAV Vector for Treatment of Achromatopsia

Applied Genetic Technologies Corporation (AGTC) is developing rAAV2tYF-PR1.7-hCNGB3, a recombinant adeno-associated virus (rAAV) vector expressing the human CNGB3 gene, for treatment of achromatopsia, an inherited retinal disorder characterized by markedly reduced visual acuity, extreme light sensit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Hum Gene Ther Clin Dev
Main Authors: Ye, Guo-jie, Budzynski, Ewa, Sonnentag, Peter, Nork, T. Michael, Miller, Paul E., McPherson, Leslie, Ver Hoeve, James N., Smith, Leia M., Arndt, Tara, Mandapati, Savitri, Robinson, Paulette M., Calcedo, Roberto, Knop, David R., Hauswirth, William W., Chulay, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851180/
https://ncbi.nlm.nih.gov/pubmed/27003752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/humc.2015.163
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados