Safety and Biodistribution Evaluation in Cynomolgus Macaques of rAAV2tYF-PR1.7-hCNGB3, a Recombinant AAV Vector for Treatment of Achromatopsia

Applied Genetic Technologies Corporation (AGTC) is developing rAAV2tYF-PR1.7-hCNGB3, a recombinant adeno-associated viral (rAAV) vector expressing the human CNGB3 gene, for treatment of achromatopsia, an inherited retinal disorder characterized by markedly reduced visual acuity, extreme light sensit...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Hum Gene Ther Clin Dev
Päätekijät: Ye, Guo-jie, Budzynski, Ewa, Sonnentag, Peter, Nork, T. Michael, Miller, Paul E., Sharma, Alok K., Ver Hoeve, James N., Smith, Leia M., Arndt, Tara, Calcedo, Roberto, Gaskin, Chantelle, Robinson, Paulette M., Knop, David R., Hauswirth, William W., Chulay, Jeffrey D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Mary Ann Liebert, Inc. 2016
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851175/
https://ncbi.nlm.nih.gov/pubmed/27003753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/humc.2015.164
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