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Trapping a Folding Intermediate of the R-Helix: Stabilization of the π-Helix
We report the design, synthesis, and characterization of a short peptide trapped in a π-helix configuration. This high-energy conformation was nucleated by a preorganized π-turn, which was obtained by replacing an N-terminal intramolecular main chain i and i + 5 hydrogen bond with a carbon-carbon bo...
Gorde:
| Argitaratua izan da: | Biochemistry |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7183248/ https://ncbi.nlm.nih.gov/pubmed/18335996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800136m |
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