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A dual effect of ursolic acid to the treatment of multiple sclerosis through both immunomodulation and direct remyelination

Current multiple sclerosis (MS) medications are mainly immunomodulatory, having little or no effect on neuroregeneration of damaged central nervous system (CNS) tissue; they are thus primarily effective at the acute stage of disease, but much less so at the chronic stage. An MS therapy that has both...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhang, Yuan, Li, Xing, Ciric, Bogoljub, Curtis, Mark T., Chen, Wan-Jun, Rostami, Abdolmohamad, Zhang, Guang-Xian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183235/
https://ncbi.nlm.nih.gov/pubmed/32253301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2000208117
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