Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis

Adult neural stem cells (aNSCs) derived from the subventricular zone of the brain show therapeutic effects in EAE, an animal model of the chronic inflammatory neurodegenerative disease MS; however, the beneficial effects are modest. One critical weakness of aNSC therapy may be an insufficient antiin...

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Detalhes bibliográficos
Main Authors: Yang, Jingxian, Jiang, Zhilong, Fitzgerald, Denise C., Ma, Cungen, Yu, Shuo, Li, Hongmei, Zhao, Zhao, Li, Yonghai, Ciric, Bogoljub, Curtis, Mark, Rostami, Abdolmohamad, Zhang, Guang-Xian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786785/
https://ncbi.nlm.nih.gov/pubmed/19884657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37914
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