Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis

Adult neural stem cells (aNSCs) derived from the subventricular zone of the brain show therapeutic effects in EAE, an animal model of the chronic inflammatory neurodegenerative disease MS; however, the beneficial effects are modest. One critical weakness of aNSC therapy may be an insufficient antiin...

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Main Authors: Yang, Jingxian, Jiang, Zhilong, Fitzgerald, Denise C., Ma, Cungen, Yu, Shuo, Li, Hongmei, Zhao, Zhao, Li, Yonghai, Ciric, Bogoljub, Curtis, Mark, Rostami, Abdolmohamad, Zhang, Guang-Xian
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2009
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786785/
https://ncbi.nlm.nih.gov/pubmed/19884657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37914
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