Hog1 activation delays mitotic exit via phosphorylation of Net1

Adaptation to environmental changes is crucial for cell fitness. In Saccharomyces cerevisiae, variations in external osmolarity trigger the activation of the stress-activated protein kinase Hog1 (high-osmolarity glycerol 1), which regulates gene expression, metabolism, and cell-cycle progression. Th...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Tognetti, Silvia, Jiménez, Javier, Viganò, Matteo, Duch, Alba, Queralt, Ethel, de Nadal, Eulàlia, Posas, Francesc
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2020
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183217/
https://ncbi.nlm.nih.gov/pubmed/32265285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1918308117
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